Madrid: Defending champion Petra Kvitova was beaten by qualifier and fellow Czech Lucie Hradecka 6-4, 6-3 in the second round of the Madrid Open on Wednesday.
World No 1 Victoria Azarenka, who lost to Kvitova in last year's final of the premier clay event, claimed her place in the quarter-finals with a 6-4, 6-4 success against Ana Ivanovic of Serbia.
Belarusian Azarenka, winner of four titles this year including her first grand slam singles at the Australian Open, needed four match points to finish off a stubborn Ivanovic.
Meanwhile, China's Li Na, the French Open champion and eighth seed, beat 12th-seeded German Angelique Kerber 7-5, 6-4.
Ivanovic, who has never been past the second round in two previous appearances in the Spanish capital, made a strong start on the blue clay of the Manolo Santana show court and conjured an early break of the Azarenka serve.
However, she tripped up at crucial moments during the remainder of the match and failed to convert three break points in the final game.
"I think she started really strong and I was a bit too slow and not aggressive enough," Azarenka said.
"I was just trying to stay in there and execute better and get some rhythm into the match."
Samantha Stosur of Australia, the fifth seed, also made it through to the last eight when she thrashed Czech Petra Cetkovska 6-3, 6-2 to set up a meeting with Hradecka or Russia's Ekaterina Makarova.
Springboard
Kvitova, the world No 4 and third seed, used her 2011 success in Madrid as a springboard for a first grand slam singles title at Wimbledon and went on to triumph at the season-ending WTA championships.
The graceful left hander has yet to win a title in 2012, however, after claiming six last season, and had her serve broken five times by Hradecka, who is ranked 105th in the world and claimed a first win against a top ten player of her career.
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