People queue to receive a dose of the Pfizer BioNTech vaccine
People queue to receive a dose of the Pfizer BioNTech vaccine at the Central Middlesex Hospital in London. Image Credit: REUTERS

JERUSALEM: Israeli researchers said they found that a three-shot course of the Pfizer/BioNTech COVID-19 vaccine provided significant protection against the new Omicron variant.

The findings were similar to those presented by BioNTech and Pfizer earlier in the week, which were an early signal that booster shots could be key to protect against infection from the newly identified variant.

The results are preliminary, with a small sample size.

The study, carried out by Sheba Medical Center and the Health Ministry’s Central Virology Laboratory, compared the blood of 20 people who had received two vaccine doses 5-6 months earlier to the same number of individuals who had received a booster a month before.

“People who received the second dose 5 or 6 months ago do not have any neutralisation ability against the Omicron. While they do have some against the Delta (strain),” Gili Regev-Yochay, director of the Infectious Diseases Unit at Sheba, told reporters.

The Israeli team said they worked with the actual virus while the companies used what is known as a pseudovirus, which was bio-engineered to have the hallmark mutations of Omicron.

The Israeli research follows a study from South Africa that found the Omicron variant can partially evade protection from two doses.