Manila: Twenty pilgrims were killed on Monday in a head-on bus collision while travelling to Christmas Day mass in the northern Philippines, police said.

A small bus taking an extended family to a dawn church service crashed into a larger bus in the town of Agoo, 200 kilometres north of Manila, killing 20 on board, Agoo police said.

The nine other occupants of the small bus were injured, as were 15 travelling on the bigger bus, police said.

"They were trying to catch a mass in Manaoag," police officer Vanessa Abubo told AFP, referring to a nearby town with a famous Catholic church.

The centuries-old Our Lady of Manaoag church is a popular pilgrimage site in the mainly Catholic nation, featuring an icon of the Virgin Mary which the faithful say performs miracles.

Agoo police chief Roy Villanueva told Manila radio station DZMM by telephone that the smaller vehicle had left its lane to overtake a third vehicle.

Authorities are investigating whether the driver, who Abubo said was among those killed, had fallen asleep or was under the influence, Villanueva added.