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'World's largest brain tumour' removed

Indian surgeons successfully remove the 'largest brain tumour in the world'

  • Digital scans show Santlal Pal's brain tumour before his operation.Image Credit: Indranil Mukherjee/AFP/Getty
  • Sanlal Pal, 31, had a 1.873 kg (4.1 lb) removed from his brain by surgeons at BYL Nair Charitable Hospital in Image Credit: Courtesy: Dr. Trimurti
  • Santlal Pal, 31, after surgery to remove his 4-pound tumourImage Credit: Courtesy: Dr. Trimurti
  • Image Credit: Dr Trimurti
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For the past several years, Santlal Pal had been watching a tumour emerge from his skull.

Doctors in India say Pal's brain tumour grew so big that it weighed nearly four pounds (1.8 kg) and measured nearly 8-by-12-by-12 inches (20 by 30 by 30 cm), according to local news reports.

BEFORE: Sanlal Pal, 31, and his 1.873-kilogram tumour before it was removed by a team headed by Dr. Trimurti Nadkarni at a government hospital in Mumbai, India

It may have been the largest brain tumour in the world.

But now it is gone: Doctors successfully removed the mass during an intensive, six-hour operation on Valentine's Day.

Dr. Trimurti Nadkarni, head of the neurosurgery department at Nair Hospital in Mumbai, told the Indian Express that the tumour "sat like a head on top of another head."

Surgeons "had to cut through the bone," Nadkarni said.

You're not going mad, you have a brain tumour!

"The sheer size of the tumour was a challenge, and we had to ensure blood pressure was maintained while surgery was on."

More than a week after the surgery, Nadkarni told BBC News that Pal, a 31-year-old shopkeeper in the state of Uttar Pradesh, is "out of danger. Now it's a matter of recovery."

3D images of the 1.873-kilogram tumour removed from Sanlal Pal, 31, at a government hospital in Mumbai, India. Dr. Trimurti Nadkarni, the surgeon who conducted the operation at BYL Nair Charitable Hospital, described the tumour as the "largest in the world" based on comparative studies conducted by his team.

The Hindu news site reported that Pal's brain tumour had been growing for several years — most rapidly in the past year.

AFTER: The head of Sanlal Pal, 31, whose 1.873-kilogram tumour was removed at a government hospital in Mumbai, India, by a team headed by Dr. Trimurti Nadkarni.

The mass was clinging to the back of Pal's head; his skull and hair grew over it. The mass appeared as large or larger than Pal's head.

Rapid growth

"In a month, it grew over an inch," his brother Akhilesh Pal told the Indian Express.

Following treatment, including chemotherapy, the mass continued to grow, Akhilesh Pal said.

"He would feel a heaviness in his head, which ached constantly, and his vision was blurred," he told the newspaper.

Pal's wife, Manju, told The Hindu that the couple consulted several doctors in Uttar Pradesh but were told that the tumour was inoperable.

Doctors said about 10 percent of the tumour was growing within Pal's skull, putting pressure on his brain and causing him to lose his eyesight; if not treated successfully, it could have caused neurological damage or paralysis.
Surgeons at Nair Hospital took it on.

"We had to cut open the scalp and remove the tumour," Nadkarni, the neurosurgeon, told the Hindu. "The part of the tumour within the skull was removed by making an opening in the skull."

Nadkarni said Pal received 11 units of blood during the operation and that, for three days after the procedure, he was on a ventilator to breathe. "Such cases are critical," the surgeon told the BBC.

Doctors are now waiting to see whether Pal will regain his eyesight. "We are praying that he regains his vision," Pal's wife told the Hindu.

There are numerous types of brain tumours, and surgical removal has its own risks.

WARNING: Viewer discretion advised

Meawwhile, below is a Youtube video uploaded by a neurosurgeon showing a live brain surgery performed on another patient to remove a large tumour.

According to the Mayo Clinic:

If the brain tumour is located in a place that makes it accessible for an operation, your surgeon will work to remove as much of the brain tumour as possible.

In some cases, tumours are small and easy to separate from surrounding brain tissue, which makes complete surgical removal possible.

In other cases, tumours can't be separated from surrounding tissue or they're located near sensitive areas in your brain, making surgery risky. In these situations your doctor removes as much of the tumour as is safe.

Even removing a portion of the brain tumour may help reduce your signs and symptoms.

Surgery to remove a brain tumour carries risks, such as infection and bleeding. Other risks may depend on the part of your brain where your tumour is located.

For instance, surgery on a tumour near nerves that connect to your eyes may carry a risk of vision loss.

Srikant Balasubramaniam, with the neurosurgery department at Nair Hospital, told the Indian Express that the medical center treats about 500 brain tumours per year, half of which are in advanced stages.

"The tumour in Pal's head grew so much because his surgery was delayed," he said.