Philadelphia: Carson Wentz tossed two touchdown passes as the NFL-leading Philadelphia Eagles beat the winless San Francisco 49ers 33-10 on a sloppy, rainy Sunday.

The Eagles (7-1) overcame a slow start on their way to a sixth straight win. The 49ers are 0-8 for the first time in franchise history.

Wentz was 18 of 32 for 211 yards and one interception. He threw a 53-yard TD pass to Alshon Jeffery and 1-yard TD pass to Zach Ertz. He leads the NFL with 19TD passes, most by an Eagles quarterback through eight games.

JuJu Smith-Schuster scored on a 97-yard touchdown pass from Ben Roethlisberger late in the third quarter and the Pittsburgh Steelers forced the Detroit Lions to turn the ball over on downs twice in a tight victory, taking the AFC North-leading Steelers to 6-2 going into their bye week.

In London, the Minnesota Vikings beat the Cleveland Browns 33-16.