Los Angeles: Khris Davis, Matt Chapman and Jed Lowrie each went deep, and the Oakland Athletics pounded out 21 hits in a 16-6 win over the Los Angeles Dodgers on Wednesday night.

The A’s sent nine batters to the plate in the fourth inning and scored five runs to lead 7-1. Marcus Semien had a two-run double during the rally, and Chapman and starting pitcher Daniel Mengden each had an RBI single.

Semien had two hits and four RBIs and extended his hitting streak to nine games. He is the only Athletics’ player to reach base in all 13 games this season. Lowrie homered in the ninth and had four RBIs.

Oakland took a 2-0 lead in the first on Davis’ two-out, two-run homer to right field. It marked only the second time this season Oakland has scored a run in the first inning and was the first homer allowed by left-hander Alex Wood this year. Davis and Jonathan Lucroy had three hits apiece.

Chapman had two hits, including his fourth homer of the season — a two-run shot in the eighth — and has seven multihit games this season to lead the majors.

Mengden (1-2) made his first career start against Los Angeles and gave up four runs over five innings.

Wood (0-2), who won a career-high 16 games last season and was sporting a 1.93 ERA, lasted 3 2/3 innings and gave up seven runs on seven hits.

Yamani Grandal had three hits and slammed a solo shot for the Dodgers in the fourth. Enrique Hernandez also homered for Los Angeles, who had their 10-game interleague winning streak snapped.