| Seed | Player | | Player | Seed |
| 1 | Djokovic (Ser) | v | Kohlschreiber (Ger) | |
| | Nieminen (Fin) | v | Hewitt (Aus) | |
| | Herbert (Fra) | v | Chung (Kor) | |
| | Struff (Ger) | v | Tomic (Aus) | 27 |
| 24 | Mayer (Arg) | v | Kokkinakis (Aus) | |
| | Tipsarevic (Ser) | v | Granollers (Spa) | |
| | Ilhan (Tur) | v | Janowicz (Pol) | |
| | Pouille (Fra) | v | Anderson (SA) | 14 |
| 9 | Cilic (Cro) | v | Moriya (Jpn) | |
| | Haider-Maurer (Aut) | v | Berankis (Ltu) | |
| | Ebden (Aus) | v | Rola (Slo) | |
| | Soeda (Jpn) | v | Isner (US) | 17 |
| 28 | Cuevas (Uru) | v | Kudla (US) | |
| | Gabashvili (Rus) | v | Zverev (Ger) | |
| | Souza (Brz) | v | Giraldo (Col) | |
| | Bolelli (Ita) | v | Nishikori (Jpn) | 5 |
| 4 | Wawrinka (Sui) | v | Sousa (Por) | |
| | Estrella Burgos (Dom) | v | Becker (Ger) | |
| | Klizan (Svk) | v | Verdasco (Spa) | |
| | Sela (Isr) | v | Thiem (Aut) | 32 |
| 19 | Robredo (Spa) | v | Millman (Aus) | |
| | Young (US) | v | Baghdatis (Cyp) | |
| | Broady (GB) | v | Matosevic (Aus) | |
| | Zeballos (Arg) | v | Goffin (Bel) | 16 |
| 11 | Dimitrov (Bul) | v | Delbonis (Arg) | |
| | Lacko (Svk) | v | Johnson (US) | |
| | De Schepper (Fra) | v | Smith (Aus) | |
| | Saville (Aus) | v | Gasquet (Fra) | 21 |
| 26 | Kyrgios (Aus) | v | Schwartzman (Arg) | |
| | Monaco (Arg) | v | Mayer (Ger) | |
| | Lajovic (Ser) | v | Haas (Ger) | |
| | Gimeno-Traver (Spa) | v | Raonic (Can) | 7 |
| 8 | Ferrer (Spa) | v | Ward (GB) | |
| | Vesely (Cze) | v | Lorenzi (Ita) | |
| | Pospisil (Can) | v | Millot (Fra) | |
| | Smyczek (US) | v | Fognini (Ita) | 30 |
| 22 | Troicki (Ser) | v | Nedovyesov (Kaz) | |
| | Stepanek (Cze) | v | Bedene (GB) | |
| | Brown (Ger) | v | Lu (Tpe) | |
| | Bellucci (Brz) | v | Nadal (Spa) | 10 |
| 13 | Tsonga (Fra) | v | Muller (Lux) | |
| | Istomin (Uzb) | v | Ramos-Vinolas (Spa) | |
| | Dolgopolov (Ukr) | v | Edmund (GB) | |
| | Ymer (Swe) | v | Karlovic (Cro) | 23 |
| 25 | Seppi (Ita) | v | Klein (GB) | |
| | Stakhovsky (Ukr) | v | Coric (Cro) | |
| | Haase (Ned) | v | Falla (Col) | |
| | Kukushkin (Kaz) | v | Murray (GB) | 3 |
| 6 | Berdych (Cze) | v | Chardy (Fra) | |
| | Krajinovic (Ser) | v | Mahut (Fra) | |
| | Gulbis (Lat) | v | Rosol (Cze) | |
| | Andujar (Spa) | v | Garcia-Lopez (Spa) | 29 |
| 18 | Monfils (Fra) | v | Carreno Busta (Spa) | |
| | Mannarino (Fra) | v | Berrer (Ger) | |
| | Sugita (Jpn) | v | Kavcic (Slo) | |
| | Almagro (Spa) | v | Simon (Fra) | 12 |
| 15 | Lopez (Spa) | v | Darcis (Bel) | |
| | Basilashvili (Geo) | v | Bagnis (Arg) | |
| | Paire (Fra) | v | Youzhny (Rus) | |
| | Bemelmans (Bel) | v | Bautista Agut (Spa) | 20 |
| 31 | Sock (US) | v | Groth (Aus) | |
| | Jaziri (Tun) | v | Duckworth (Aus) | |
| | Querrey (US) | v | Sijsling (Ned) | |
| | Dzumhur (Bih) | v | Federer (Sui) | 2 |
