Houston: Authorities say a Saudi woman who was travelling by plane to Houston from Qatar to seek medical treatment died en route.

The Houston Chronicle reports 49-year-old Fatima M. Al Siari, a Saudi, was onboard a nonstop flight from Doha, Qatar, when she died.

Houston police spokeswoman Jodi Silva says the Qatar Airways flight landed at George Bush International airport about 4.30pm on Friday.

A physician aboard the plane tended to Fatima but could not help her. It was not known if the doctor was accompanying her.

It was not immediately known what condition the woman had or which hospital in the Texas Medical Centre she planned to visit.

Silva said Fatima apparently died of natural causes but an official determination will be made by a medical examiner.