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FILE - This Oct. 12, 2012 file image released by Starpix shows Marvel Comics scribe and film producer Stan Lee at a special signing, hosted by Choice Collectibles, a publisher of Marvel fine art, during New York Comic Con at Jacob K. Javits Convention Center in New York. Lee is missing in action at Comic-Con International, held July 24-27, 2014, in San Diego. A spokesman for the 91-year-old co-creator of such comic book superheros as The Avengers, X-Men and Spider-Man says Lee lost his voice because of laryngitis and is unable to attend the four-day pop-culture celebration. (AP Photo/Starpix, Marion Curtis, file) Image Credit: AP

Stan Lee is missing in action at Comic-Con.

A spokesman for the 91-year-old co-creator of superheros such as The Avengers, X-Men and Spider-Man says Lee lost his voice because of laryngitis. He added that Lee is otherwise in good health and is disappointed he’s missing the celebration.

The former Marvel Comics editor-in-chief has been a constant presence at San Diego Comic-Con since the convention launched in the 1970s.

Lee was scheduled to appear on Friday and Saturday to sign autographs and unveil the latest instalment of in his Stan Lee’s Kids Universe multimedia project.

Comic-Con is a four-day festival celebrating film, TV, video games, comic books, costumes and other popular arts. It kicked off on Thursday and continues through Sunday at the San Diego Convention Centre.