Dera Ismail Khan: A suspected US drone fired at least one missile into Pakistan on Thursday, Pakistani intelligence officials said.
The missile struck a house in the Sam village of South Waziristan which borders Afghanistan.
"There may be casualties, we are checking," said an intelligence official, who declined to be identified.
Another official said two missiles were fired on Thursday.
"Drones are still flying in the area. No one is going close as they fear more missiles could be fired," the second official said.
The first official said the area had been cordoned off by militants.
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