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Prostate cancer deaths fall after screening
Prostate cancer deaths fell substantially in the decade after one Austrian state began free PSA screening tests for all men ages 45 to 75, according to a new study.
- Reuters
- Published: 00:03 May 13, 2008
Prostate cancer deaths fell substantially in the decade after one Austrian state began free PSA screening tests for all men ages 45 to 75, according to a new study.
Researchers found that after the state of Tyrol began a programme of free PSA screening and prostate cancer treatment in 1993, the expected death rate from prostate cancer dropped by 54 per cent. That compared with a decline of 29 per cent in the rest of Austria, where free screening was not available.
The findings, reported in the journal BJU International, suggest that routine PSA testing can save men's lives - something that has long been an open question.
PSA tests measure the amount of a protein called prostate-specific antigen in a man's blood. Because prostate tumours cause PSA levels to rise, routine PSA testing can catch the cancer early.
But PSA screening is controversial because it is not clear that the benefits outweigh the risks. Prostate cancer is often very slow-growing, and PSA screening may lead to treatment of tumours that would never have become life-threatening; treatment can carry side effects, like incontinence and erectile dysfunction.
Increase
In addition, PSA concentrations can increase for a reason other than prostate cancer and confirmation of prostate cancer requires a biopsy of the prostate gland, which itself can have side effects, such as infection or bleeding.
However, in the current study, early detection through widespread PSA screening is likely the driving force behind the greater drop in death rates seen in Tyrol, according to the researchers.
Declined
Between 1993 and 2005, nearly 87 per cent of men ages 45 to 75 in Tyrol had at least one PSA screening test, the study found. That was up from 11 per cent before the free programme began.
And while prostate cancer death rates declined throughout Austria during the same period, they fell faster in Tyrol.
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