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Ava DuVernay Image Credit: Supplied

Ava DuVernay’s history-making adaptation of A Wrinkle in Time has officially kicked off production in Los Angeles.

Based on the Newbery Medal-winning novel by Madeleine L’Engle, A Wrinkle in Time follows young Meg Murray and her younger brother Charles Wallace as they travel through space and time to search of their missing father. Joining them in their adventure is Meg’s friend Calvin.

DuVernay commemorated the start of A Wrinkle in Time’s filming with a tweet.

With A Wrinkle in Time, DuVernay is the first woman of colour to direct a live-action film with a production budget over $100 million (Dh367.29 million). Much of the big-budget Disney adaptation will be shot in and around the Los Angeles area and is one of 28 movie projects selected under California’s film and television tax credit program.

According to state officials, A Wrinkle in Time will bring in $85 million in qualified spending to California and receive an incentive of $18 million, the largest since the state program expanded in 2014.

Storm Reid will star in the film as Meg, which will also feature Oprah Winfrey, Reese Witherspoon and Mindy Kaling as Mrs Which, Mrs Whatsit and Mrs Who, respectively. Gugu Mbatha-Raw, Chris Pine, Zach Galifianakis and Levi Miller are also a part of the cast.

The film is scheduled for a 2018 release.